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A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
Published on: September 9, 2016
1,3-Dimethylisoguanine, a new purine from the marine sponge Amphimedon viridis
C C Chehade1, R L Dias, R G Berlinck
1Instituto de Química de São Carlos, Universidade de São Paulo, Brazil.
Journal of Natural Products
|July 1, 1997
Abstract:
A new purine, 1,3-dimethylisoguanine (1), has been isolated from the marine sponge Amphimedon viridis and identified by analysis of spectroscopic data. Compound 1 increased the contractions obtained by transmural electrical stimulation in the guinea pig longitudinal muscle/myenteric plexus in a dose-dependent manner.

