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Related Experiment Videos

Establishing a cancer risk evaluation program

K A Calzone1, J Stopfer, A Blackwood

  • 1University of Pennsylvania Cancer Center, Department of Medicine, Philadelphia, USA.

Cancer Practice
|July 1, 1997
PubMed
Summary
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This program offers genetic testing for cancer susceptibility, addressing complex ethical and clinical issues. It successfully meets participant needs and ensures adherence to guidelines for cancer risk assessment and management.

Area of Science:

  • Oncology
  • Genetics
  • Medical Ethics

Background:

  • Presymptomatic genetic testing for cancer susceptibility presents complex challenges.
  • A structured approach is needed to manage these complexities.

Purpose of the Study:

  • To present a model for a cancer risk evaluation program.
  • This program specifically addresses issues unique to genetic testing for cancer risk.

Main Methods:

  • The Cancer Risk Evaluation Program offers clinical and psychosocial assessment, education, and genetic counseling.
  • It includes cancer risk analysis, predisposition genetic testing when appropriate, and long-term surveillance.
  • The program also facilitates ongoing genetic and clinical research.

Main Results:

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  • Program evaluations indicate successful fulfillment of participant needs.
  • The program ensures University of Pennsylvania Cancer Center's cancer genetic services align with established guidelines.
  • This includes adherence to indications for genetic testing and informed consent procedures.

Conclusions:

  • Anticipated demand for predisposition genetic testing for cancer susceptibility is substantial.
  • Clinical programs must address the complexities of presymptomatic genetic testing and integrate cancer risk assessment strategies.
  • Healthcare providers need to be informed about cancer risk assessment, genetic testing, and associated ethical, legal, and social issues.