Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Abutment region dosimetry for sequential arc IMRT delivery

D A Low1, S Mutic

  • 1Mallinckrodt Institute of Radiology, Division of Radiation Oncology, St Louis, MO 63110, USA.

Physics in Medicine and Biology
|July 1, 1997
PubMed
Summary

Sequential arc intensity modulated radiation therapy (IMRT) can cause dose inaccuracies far from the isocenter. This study found significant dose variations in abutment regions, necessitating further investigation for improved treatment planning.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute impact of aerobic exercise on local cutaneous thermal hyperaemia.

Microvascular research·2022
Same author

The effects of exercise training in the cold on cerebral blood flow and cerebrovascular function in young healthy individuals.

Autonomic neuroscience : basic & clinical·2022
Same author

An Adaptive Low-Rank Modeling-Based Active Learning Method for Medical Image Annotation.

Ingenierie et recherche biomedicale : IRBM = Biomedical engineering and research·2021
Same author

Oxynet: A collective intelligence that detects ventilatory thresholds in cardiopulmonary exercise tests.

European journal of sport science·2020
Same author

A mechanistic study of the tremor associated with epidural anaesthesia for intrapartum caesarean delivery.

International journal of obstetric anesthesia·2020
Same author

McSART: an iterative model-based, motion-compensated SART algorithm for CBCT reconstruction.

Physics in medicine and biology·2019

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Radiotherapy Technology

Background:

  • Arc-based intensity modulated radiation therapy (IMRT) is commercially available.
  • Accurate patient positioning is crucial for IMRT delivery near the gantry isocenter.
  • Beam divergence in arc treatments less than 360 degrees can cause dose heterogeneities away from the isocenter.

Purpose of the Study:

  • To characterize dose distribution heterogeneities in abutment regions during sequential arc IMRT delivery.
  • To investigate the impact of off-axis positions on dose variations.
  • To evaluate the accuracy of current treatment planning software in predicting these heterogeneities.

Main Methods:

  • Five IMRT dose distributions were optimized for 8 cm diameter targets at varying distances from the isocenter.

Related Experiment Videos

  • Arc delivery was limited to 290 degrees, symmetric about the vertical axis.
  • Dose in abutment regions was measured using film and analyzed along vertical and horizontal axes.

    • Main Results:

    • Dose heterogeneity showed little dependence on the horizontal axis through the isocenter.
    • Abutment regions 7 cm above and below the isocenter exhibited 15% low dose and 7% high dose, respectively.
    • Current treatment planning software did not predict these observed dose heterogeneities.

    Conclusions:

    • Sequential arc IMRT delivery can result in significant dose heterogeneities in abutment regions, particularly along the vertical axis.
    • These findings highlight limitations in current treatment planning algorithms for arc-based IMRT.
    • The observed dose variations warrant further investigation to ensure accurate and effective radiation therapy.