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Bilateral clinical anophthalmos

A Young1, M O'Keefe

  • 1Department of Paediatric Ophthalmology, The Children's Hospital, Dublin, Ireland.

Acta Ophthalmologica Scandinavica
|June 1, 1997
PubMed
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Bilateral clinical anophthalmos in five children showed no links to pregnancy, environment, or family history. However, the condition was strongly associated with multiple systemic abnormalities.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Medical Genetics

Background:

  • Bilateral clinical anophthalmos is a rare congenital condition.
  • Understanding its etiology and associated conditions is crucial for patient management.

Purpose of the Study:

  • To investigate the risk factors, associations, and outcomes in a cohort of children with bilateral clinical anophthalmos.
  • To identify potential etiological links and co-occurring systemic abnormalities.

Main Methods:

  • Retrospective case series analysis of five children diagnosed with bilateral clinical anophthalmos.
  • Review of clinical data, including gestational, environmental, and hereditary factors.
  • Assessment for associated systemic abnormalities.

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Main Results:

  • No significant gestational, environmental, or hereditary risk factors were identified.
  • A strong association was observed between bilateral clinical anophthalmos and multiple systemic abnormalities.
  • Outcomes varied among the affected children.

Conclusions:

  • Bilateral clinical anophthalmos in this cohort appears to be primarily associated with systemic abnormalities rather than identifiable external or hereditary factors.
  • Further research is needed to elucidate the complex etiology and management strategies for this condition.