[The adjuvant chemotherapy of N(-) patients with breast cancer--when is it indicated?]

The object of this research is determination the necessity of leading of adjuvant chemotherapy with patients with breast cancer without metastases in axillary lymph nodes (N(-)), with disadvantages other prognostic factors (T > 20 mm, estrogen receptors (-), II and III stage grading). Post-operative with 52 women with high risk of recedives or metastases had been performed polychemotherapy (39-CMF and 13 FEC). Control group include 40 patients without adjuvant chemotherapy. Relapse are report with 6 of investigate and 8 of control group (pt > 0.05). The obtained results are discussed in connection with literature data.