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Incrustation and uptake of skeletal imaging agent in transitional cell carcinoma
M Taniguchi1, N Tatsuta, H Yokota
1Department of Radiology, Kanazawa Medical University Hospital, Kahoku-gun, Japan.
Abstract:
We present a case of transitional cell carcinoma of the bladder visualized by 99mTc-HMDP bone scintigraphy and suggest possible uptake mechanisms. Pelvic CT demonstrated a sessile bladder tumor with punctate and curvilinear calcifications on the surface areas (incrustation). Technetium-99m-HMDP bone scintigraphy demonstrated intense uptake corresponding to the site of the bladder tumor. Chemisorption of urinary 99mTc-HMDP, rather than of blood-born 99mTc-HMDP, may have occurred at the tumor surface.