Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma

¹Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine

|August 1, 1997

Abstract:

Experience of scintigraphic detection of bone lesion and active bone marrow involvement of multiple myeloma, especially with sestamibi and FDG-PET scans is in evolution. We report a case of intense sestamibi uptake in bone marrow correlating with the extent of the disease, while FDG-PET scans showed activity only in areas of active disease progression associated with pain. Technetium-99m-sestamibi appears to indicate the extent of the disease, while [18F]FDG-PET scans show sites of active tumor proliferation and may be useful in directing local therapy such as radiation.

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Abstract:

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