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Leukocyte-marrow scintigraphy in hyperostosis frontalis interna
1Division of Nuclear Medicine, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA.
Summary
Hyperostosis frontalis interna, a frontal bone thickening, can show asymmetric leukocyte uptake. Marrow scintigraphy confirmed this activity was due to active marrow, not infection, in a unique case.
Area of Science:
- Medical Imaging
- Skeletal Biology
- Nuclear Medicine
Background:
- Hyperostosis frontalis interna (HFI) involves thickening of the frontal bones, increasing diploic space and active marrow.
- Leukocyte uptake in HFI is typically symmetric, suggesting a benign etiology.
- Asymmetric uptake can mimic infectious or neoplastic processes.