Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Does oligoantigenic diet influence hyperactive/conduct-disordered children--a controlled trial

M H Schmidt1, P Möcks, B Lay

  • 1Central Institute of Mental Health, Department of Child and Adolescent Psychiatry, Mannheim, Germany.

European Child & Adolescent Psychiatry
|June 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurement of 24-h continuous human CH<sub>4</sub> release in a whole room indirect calorimeter.

Journal of applied physiology (Bethesda, Md. : 1985)·2023
Same author

SAS CARE 1: Sleep architecture changes in a cohort of patients with Ischemic Stroke/TIA.

Sleep medicine·2022
Same author

A circuit perspective on narcolepsy.

Sleep·2020
Same author

Secondary colonic stent insertion in acute large bowel obstruction following primary stent failure.

Annals of the Royal College of Surgeons of England·2019
Same author

Temporomandibular disorders and psychosocial status in osteogenesis imperfecta - a cross-sectional study.

BMC oral health·2018
Same author

Involuntary psychiatric hospitalisation, stigma stress and recovery: a 2-year study.

Epidemiology and psychiatric sciences·2018
Same journal

Altered intrinsic connectivity in default mode and somatomotor networks in children and adolescents with ADHD: a neuroimaging meta-analysis.

European child & adolescent psychiatry·2026
Same journal

From cradle to Tic: early developmental profiles of tourette syndrome and its comorbidities in the MoBa cohort.

European child & adolescent psychiatry·2026
Same journal

The role and application of task-state fNIRS in identifying biomarkers in children and adolescents with ADHD: a systematic review.

European child & adolescent psychiatry·2026
Same journal

Sensory processing and neurodevelopmental disorder traits in 4- to 5-year-old Dutch children adjusted for sex, neurodevelopment in infancy and IQ.

European child & adolescent psychiatry·2026
Same journal

Extending prenatal perspectives: perinatal and neonatal physiological states in the early etiology of childhood ADHD.

European child & adolescent psychiatry·2026
Same journal

Emergency presentations following youth suicide attempts during the COVID-19 pandemic: temporal trends and associations with containment measures.

European child & adolescent psychiatry·2026
See all related articles

An oligoantigenic diet improved behavior in 24% of children with hyperactive/disruptive disorder, though less effectively than methylphenidate. This dietary approach warrants further research for treating such behavioral conditions.

Area of Science:

  • Child and Adolescent Psychiatry
  • Nutritional Psychiatry
  • Behavioral Science

Background:

  • Hyperactive/disruptive behavior disorder affects numerous children, impacting their development and daily functioning.
  • Current treatments include stimulant medication, but alternative or complementary therapies are sought.
  • Dietary interventions are increasingly explored for their potential impact on behavior.

Purpose of the Study:

  • To evaluate the efficacy of an oligoantigenic diet in children diagnosed with hyperactive/disruptive behavior disorder.
  • To compare the effectiveness of the oligoantigenic diet with methylphenidate (a common stimulant medication).
  • To assess behavioral changes across various standardized situations.

Main Methods:

  • A crossover, placebo-controlled, double-blind study design was employed.

Related Experiment Videos

  • Participants included 49 children with hyperactive/disruptive behavior disorder.
  • Behavioral assessments were conducted by trained raters in standardized settings, including cognitive tasks, free play, and school environments.
  • Main Results:

    • Twelve children (24%) demonstrated significant behavioral improvements on the oligoantigenic diet compared to a control diet.
    • Methylphenidate treatment resulted in a higher response rate (44%) compared to the diet.
    • Children who received both treatments showed comparable positive behavioral changes.

    Conclusions:

    • The oligoantigenic diet can be an effective treatment for a subset of children with hyperactive/disruptive behavior disorder.
    • While not universally effective, dietary interventions represent a viable therapeutic avenue that merits further investigation.
    • Further research is needed to identify predictors of response and optimize dietary strategies for behavioral disorders.