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Surface studies of albumin immobilized onto PE and PVC films
A A de Queiroz1, E R Barrak, H A Gil
1Escola Federal de Engenharia de Itajubá, Instituto de Ciëncias, Brazil.
Journal of Biomaterials Science. Polymer Edition
|January 1, 1997
Abstract:
The aim of this study is to evaluate the thrombogenic behaviour of the low density polyethylene and poly(vinyl chloride) modified by radiation-grafting technique. After copolymerization with acrylic acid by gamma-rays from a 60Co source, BSA was immobilized onto functionalized graft copolymers. The biological interaction between these materials and blood was studies by in vitro methods. The BSA immobilization effectively suppressed the adhesion and activation of platelets when it contacted whole blood.