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Case report: haemorrhagic colitis associated with royal jelly intake
Y Yonei1, K Shibagaki, N Tsukada
1Department of Internal Medicine, Nippon Kokan Hospital, Kanagawa, Japan.
Journal of Gastroenterology and Hepatology
|July 1, 1997
Summary
Royal jelly consumption may cause hemorrhagic colitis, a condition involving intestinal bleeding and inflammation. This case report highlights a potential adverse effect of royal jelly, emphasizing the need for awareness among consumers and healthcare providers.
Area of Science:
- Gastroenterology
- Toxicology
- Immunology
Background:
- Royal jelly is a honey bee secretion used as a dietary supplement.
- Adverse effects of royal jelly are rarely reported.
- Hemorrhagic colitis is a severe form of inflammation of the colon.
Observation:
- A 53-year-old woman developed abdominal pain and bloody diarrhea after consuming royal jelly for 25 days.
- Colonoscopy revealed diffuse hemorrhagic and edematous sigmoid colon mucosa.
- Histopathology showed mucosal hemorrhage, edema, and inflammatory cell infiltration, with platelet aggregation in capillaries.
Findings:
- Drug-induced lymphocyte stimulation test was positive for royal jelly.
- The patient's symptoms resolved with conservative therapy.
- Colonic lesions healed within two weeks.
Implications:
- This is the first reported case linking royal jelly intake to hemorrhagic colitis.
- Highlights a potential adverse reaction to royal jelly, necessitating further investigation.
- Informs healthcare providers and consumers about potential risks associated with royal jelly supplements.