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Synchronized Plasmodium yoelii yoelii: pattern of gametocyte production, sequestration and infectivity
P Gautret1, F Miltgen, A G Chabaud
1Laboratoire de Biologie Parasitaire et de Chimiothérapie, CNRS (ERS 156), Paris, France.
Parassitologia
|December 1, 1996
Abstract:
The chronobiology of the gametocytes of P. yoelii was studied in Percoll-glucose synchronized infection in the mouse. The gametocyte developmental cycle consisted of 4 successive stages: stage 0 maturation took 27 hours from merozoite invasion, stage 0 to stage 1 lasted 6 hours, stage I to stage II and stage II to stage III lasted 3 hours each. Stage 0 gametocytes were found to sequester in small peripheral capillaries, and the number of oocysts in mosquitoes was related to the number of stage 0 gametocytes ingested.