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Facilitated analysis of data on drug regimen compliance
E de Klerk1, S van der Linden, D van der Heijde
1Department of Internal Medicine, University Hospital Maastricht, The Netherlands.
Statistics in Medicine
|July 30, 1997
Abstract:
Drug actions depend on dose and intervals between doses, in ways that are drug-specific and sometimes complex, complicating the use of drug dosing histories as an explanatory variable in the analysis of clinical trials. We describe a spread-sheet method for conveniently displaying patients' drug dosing histories, to facilitate identification of dosing correlates of clinically important events.