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Updated: Aug 19, 2026
An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
Palliative effect of intravesical bacillus Calmette-Guerin in elderly patients with advanced bladder carcinoma
S Holmäng1, M Fehrling, H Hedelin
1Department of Urology, Sahlgrenska University Hospital, Göteborg, Sweden.
Purpose:
Intravesical bacillus Calmette-Guerin (BCG) was used to palliate severe local symptoms in patients with invasive carcinoma.
Materials And Methods:
Four patients with unresectable bladder carcinoma who were unfit for radical cystectomy because of age and poor performance status were treated with a 6-week course of BCG followed by monthly instillations.
Results:
Urgency and frequency were reduced in 3 patients and the improvement lasted for 9 to 19 months. All 4 patients ultimately died of bladder carcinoma.
Conclusions:
The results of palliative BCG treatment were encouraging, but further experience is necessary.
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