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Related Experiment Videos

Transrectal prostate ultrasonography: variability of interpretation

M I Resnick1, J A Smith, P T Scardino

  • 1Department of Urology, Case Western Reserve University, Cleveland, Ohio, USA.

The Journal of Urology
|September 1, 1997
PubMed
Summary

The study compared transrectal ultrasound interpretations for prostate cancer staging. The operator performing the exam showed better accuracy than reviewers, especially when clinical data was unavailable, highlighting the importance of technical quality.

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Area of Science:

  • Urology
  • Radiology
  • Oncology

Background:

  • Transrectal ultrasound (TRUS) is crucial for prostate cancer staging.
  • Interpreting TRUS findings can have variability among clinicians.
  • Assessing the impact of clinical data on interpretation accuracy is important.

Purpose of the Study:

  • To compare the accuracy of TRUS interpretation by the performing operator versus independent reviewers.
  • To evaluate the effect of clinical data availability on interpretation accuracy.
  • To assess inter-observer and intra-observer variability in TRUS interpretation for prostate cancer.

Main Methods:

  • Patients undergoing radical prostatectomy for localized prostate cancer had pre-operative TRUS.
  • TRUS interpretations were performed by the operator and by experienced reviewers (with and without clinical data).

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  • Ultrasound staging was compared with final pathological findings from prostatectomy specimens.

    • Main Results:

    • Operator accuracy for extracapsular extension and seminal vesicle invasion was 0.70 and 0.74.
    • Reviewer accuracy ranged from 0.59-0.75 for extracapsular extension and 0.44-0.74 for seminal vesicle invasion.
    • Blinded reviews were generally less accurate than unblinded reviews, with statistical significance in some cases.

    Conclusions:

    • The performing operator demonstrated an advantage in interpretation accuracy, particularly without clinical data.
    • Clinical data did not consistently improve interpretation accuracy for most reviewers.
    • Higher technical quality of the TRUS examination correlated with improved reading accuracy.