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Chronic viral funisitis

C Navarro, W A Blanc

    The Journal of Pediatrics
    |December 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Chronic funisitis, a rare umbilical cord inflammation, is linked to intrauterine viral infections. This condition presents distinct features and is associated with adverse fetal outcomes.

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    Area of Science:

    • Pathology
    • Perinatology
    • Infectious Diseases

    Background:

    • Chronic funisitis is a rare umbilical cord inflammation.
    • This study compares chronic funisitis with acute and subacute forms.

    Observation:

    • Distinctive findings include lymphoplasmocytic infiltration and vascular media necrosis with calcification.
    • Chronic funisitis was unusually associated with chronic chorioamnionitis and chronic villitis.
    • Viral inclusions were identified in three placentas.

    Findings:

    • One fetus was stillborn, one aborted, and two live-born.
    • Two fetuses experienced growth retardation, and three showed evidence of infection.
    • The observed features suggest chronic intrauterine viral infection as the cause.

    Implications:

    • This research highlights the link between chronic funisitis and intrauterine viral infections.
    • Understanding these associations is crucial for diagnosing and managing adverse pregnancy outcomes.
    • Further research into viral pathogenesis in placental inflammation is warranted.