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MR demonstration of cerebral hemimegalencephaly associated with cerebellar involvement (total hemimegalencephaly)
1Department of Radiology, Ege University Hospital, Bornova, Izmir, Turkey.
Abstract:
Hemimegalencephaly or unilateral megalencephaly is a rare malformation characterized by overdevelopment of all or part of one cerebral hemisphere. Although previous pathological studies noted an associated overdevelopment of the ipsilateral cerebellar hemisphere in a few cases, to the best of the author's knowledge, such an association has not yet been reported in the radiological literature. This paper reports a 1-yr-old patient with hemimegalencephaly of the right cerebral hemisphere, and hemimegalencephaly of the ipsilateral cerebellar hemisphere. The ipsilateral half of the brainstern was also enlarged. This condition is suggested to be labelled as "total hemimegalencephaly".
Insights
Hemimegalencephaly, a rare brain overdevelopment condition, can affect the cerebellum. This study reports a case of unilateral cerebral and cerebellar hemisphere enlargement, proposing the term "total hemimegalencephaly".
Area of Science:
- Neurology
- Radiology
- Pathology
Background:
- Hemimegalencephaly is a rare congenital malformation involving unilateral cerebral hemisphere overgrowth.
- Previous pathological studies have occasionally noted ipsilateral cerebellar hemisphere overdevelopment.
- Radiological literature has not extensively documented this specific association.