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Updated: Aug 12, 2026

Impression Cytology of the Lid Wiper Area
Published on: August 9, 2016
Cytologic diagnosis of Ki-1 lymphoma in pleural and peritoneal effusions: a case report
I T Burja1, S K Thompson, E J Brown
1Cytopathology Section, Veterans Administration Medical Center, Johnson City, Tennessee, USA.
Abstract:
This is a report of a case of Ki-1-positive large-cell anaplastic lymphoma in an 87-year-old man diagnosed on pleural and peritoneal fluids by cytomorphologic and immunohistochemical examination. Papanicolaou-stained smears revealed many single, large neoplastic cells containing one or two nuclei with occasional multinucleated cells having a wreath-like nuclear arrangement. The tumor cells expressed Ki-1 antigen and epithelial membrane antigen. This is the first known report of Ki-1 lymphoma diagnosed initially on cytologic examination of pleural and peritoneal fluids.
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