Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interactions between pulse separation and pulse polarity order in cochlear implants

A L Miller1, D J Morris, B E Pfingst

  • 1Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan Medical Center, Ann Arbor 48109-0506, USA.

Hearing Research
|July 1, 1997
PubMed
Summary

Electrical stimulation of the cochlea shows that alternating pulse polarity significantly lowers detection thresholds at short pulse separations in nonhuman primates. These findings offer insights into neural mechanisms of auditory perception.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effects of pasteurization on caseinate-based edible film solutions.

Journal of dairy science·2026
Same author

Wastewater treatment techniques for application in fat recovery from waste ice cream.

Journal of dairy science·2026
Same author

Lead exposure, glucocorticoids, and physiological stress across the life course: A systematic review.

Environmental pollution (Barking, Essex : 1987)·2024
Same author

Associations of prenatal and childhood Pb exposure with allostatic load in adolescence: Findings from the ELEMENT cohort study.

Environmental research·2023
Same author

Search for Subsolar-Mass Binaries in the First Half of Advanced LIGO's and Advanced Virgo's Third Observing Run.

Physical review letters·2022
Same author

A predictive model for elemental carbon, organic carbon and total carbon based on laser induced breakdown spectroscopy measurements of filter-collected diesel particulate matter.

Spectrochimica acta. Part B, Atomic spectroscopy·2021

Area of Science:

  • Neuroscience
  • Auditory Electrophysiology
  • Sensory Perception

Background:

  • Understanding electrical detection thresholds is crucial for developing effective cochlear implants.
  • Psychophysical studies in nonhuman primates provide valuable models for human auditory processing.

Purpose of the Study:

  • To investigate the interaction between pulse separation and pulse polarity order on electrical detection thresholds.
  • To compare threshold vs. pulse separation functions for constant and alternating leading phase polarities.

Main Methods:

  • Psychophysical studies were conducted on nonhuman primates trained with acoustic stimuli.
  • Subjects received unilateral cochlear implantation for electrical stimulation.
  • Threshold vs. pulse separation functions were measured for biphasic electrical pulse trains with varying polarity conditions.

Related Experiment Videos

Main Results:

  • Constant leading phase polarity resulted in nonmonotonic (U-shaped) threshold functions.
  • Alternating leading phase polarity significantly reduced thresholds at short pulse separations (<1 ms), yielding monotonic functions.
  • Polarity effects were more pronounced with longer pulse trains and durations.

Conclusions:

  • Alternating pulse polarity can enhance electrical detection sensitivity, particularly at short inter-pulse intervals.
  • Neural mechanisms like refractory properties and residual potentials likely underlie these observed polarity effects.
  • Findings have implications for optimizing electrical stimulation strategies in cochlear implant technology.