RNA processing: pocket guides to ribosomal RNA

¹Genetics and Biochemistry Branch, NIDDK, NIH, Bethesda, Maryland 20892, USA.

|August 1, 1997

Abstract:

The functional role of a recently identified class of small nucleolar (sno) RNAs has been elucidated: the 'box H/ACA' snoRNAs act as guide RNAs, specifying the position of evolutionarily conserved pseudouridines in ribosomal (r)RNA via an rRNA-snoRNA base-pairing interaction that forms a 'pseudouridine pocket'.

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