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Incidence and frequency rates of childhood cancer in Namibia
1Department of Paediatrics and Child Health, University of Stellenbosch, Tygerberg, W Cape.
Insights
Childhood cancer incidence in Namibia is lower than in developed nations, with central nervous system tumours being most common. Cancer rates show a mix of African and industrialised country patterns.
Area of Science:
- Paediatric Oncology
- Epidemiology
- Global Health
Background:
- Childhood cancer presents a significant global health challenge, with varying incidence and patterns across different regions.
- Understanding the epidemiology of paediatric malignancies is crucial for resource allocation and targeted interventions.
Purpose of the Study:
- To determine the incidence and frequency of paediatric malignancies in Namibia.
- To compare these findings with established childhood cancer rates in other countries.
Main Methods:
- A retrospective descriptive study was conducted using a 6-year survey of childhood cancer data in Namibia (1983-1988).
- Incidence and frequency rates were calculated for 163 children under 15 years diagnosed with malignant neoplasms, intracranial tumours, or histiocytosis.
Main Results:
- The overall childhood cancer incidence in Namibia was 55.5 per million children.
- Central nervous system tumours were the most frequent (18%), followed by renal tumours (14%), leukaemia (12%), and lymphoma (11.5%).
- Incidence rates for retinoblastoma, renal tumours, bone tumours, and soft-tissue sarcomas showed similarities to rates in other African countries or Western nations, while leukaemia and lymphoma rates were lower than in central Africa or developed countries.
Conclusions:
- The incidence patterns of childhood cancer in Namibia exhibit characteristics of both African and industrialised country profiles.
- These findings highlight the unique epidemiological landscape of paediatric malignancies in sub-Saharan Africa.
Objective:
To estimate the extent of paediatric malignancy in an African country and to compare these findings with paediatric cancer rates in other countries.
Design:
A retrospective descriptive study which calculated incidence and frequency rates from the data obtained from a 6-year survey of childhood cancer in Namibia.
Setting:
Children from the general community who were referred by primary care physicians or clinics and diagnosed in peripheral district hospitals or a tertiary care institution.
Patients:
A total of 163 children less than 15 years of age diagnosed with any malignant neoplasm, intracranial tumour or histiocytosis between 1983 and 1988.
Intervention:
None.
Main Outcome Measures:
The minimum overall incidence of childhood cancer recorded in Namibia was lower than the rates usually reported by economically privileged countries. The rates of certain malignancies corresponded to the rates recorded in other African countries.
Results:
The overall incidence of childhood cancer was 55.5 per million. Tumours of the central nervous system occurred most commonly (18%), followed by renal tumours (14%), leukaemia (12%) and lymphoma (11.5%). The 5.8 per million incidence rate of retinoblastoma was similar to the rates recorded in other African countries but higher than in the UK or the USA. The incidence rates per million children for renal tumours, malignant bone tumours and soft-tissue sarcomas were 7.4, 4.8 and 5.2, respectively, which correspond with the rates in Western Europe and the USA. The incidence rate of CNS tumours was only 9.3 per million. Both leukaemia (6.5 per million) and lymphoma (6.3 per million) had rates far lower than those recorded in central Africa or developed Western countries.
Conclusion:
The incidence pattern of childhood cancer in Namibia demonstrates features of both the patterns described as typical for Africa and those described for industrialised countries.
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