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Neonatal renal failure due to obstructive candidal bezoars
P Hari1, A Srivastava, A K Gupta
1Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Pediatric Nephrology (Berlin, Germany)
|August 1, 1997
Summary
Infant acute renal failure (ARF) caused by fungal balls obstructing the kidneys resolved after treatment. Renal decompression and antifungal medications successfully treated the infant
Area of Science:
- Pediatric Nephrology
- Mycology
- Infectious Diseases
Background:
- Neonatal sepsis and respiratory distress are common in infants.
- Broad-spectrum antibiotic use can increase the risk of fungal infections.
- Fungal bezoars are rare causes of urinary tract obstruction.
Observation:
- A 7-week-old infant presented with acute renal failure (ARF).
- The ARF was attributed to bilateral candidal bezoars obstructing the pelviureteric junction.
- The infant had a history of respiratory distress and septicemia treated with antibiotics.
Findings:
- Renal decompression via bilateral nephrostomy tube placement was performed.
- Parenteral administration of amphotericin B and 5-flucytosine was initiated.
- Successful recovery from ARF was observed following treatment.
Implications:
- This case highlights fungal bezoars as a critical cause of ARF in infants.
- Prompt diagnosis and combined antifungal and surgical management are crucial for favorable outcomes.
- Understanding the link between antibiotic use and invasive fungal infections in neonates is important.