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Features associated with painless peptic ulcer bleeding

C M Wilcox1, W S Clark

  • 1Emory University School of Medicine, and the Medical Service of Grady Memorial Hospital, Atlanta, Georgia, USA.

The American Journal of Gastroenterology
|August 1, 1997
PubMed
Summary
This summary is machine-generated.

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Nearly half of patients with bleeding peptic ulcers experience no abdominal pain. Larger ulcers, tobacco use, and younger age (<80 years) are linked to pain in these cases.

Area of Science:

  • Gastroenterology
  • Internal Medicine

Background:

  • Painless peptic ulcer bleeding is a recognized clinical entity.
  • Limited research exists on clinical features associated with the absence of abdominal pain in peptic ulcer bleeding.

Purpose of the Study:

  • To investigate the prevalence and clinical correlates of abdominal pain in patients with upper gastrointestinal bleeding due to peptic ulcers.

Main Methods:

  • Prospective evaluation of patients admitted for upper GI bleeding.
  • Data collection included patient-reported pain, dyspepsia, and clinical/endoscopic features.
  • Peptic ulcer bleeding was confirmed endoscopically; malignant ulcers were excluded.

Main Results:

  • 449 patients with peptic ulcer bleeding were analyzed; 43% reported no abdominal pain.

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  • Pain absence showed no correlation with race, gender, alcohol, ulcer location, NSAID use, ulcer history, or comorbidity.
  • Pain presence correlated with larger ulcer size (>2 cm), tobacco use, and age <80 years.
  • Conclusions:

    • Approximately 50% of bleeding peptic ulcer patients lack abdominal pain.
    • Key determinants of ulcer-related pain include large ulcer size, tobacco consumption, and younger age (<80 years).