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Separation of carp (Cyprinus carpio L.) thrombocytes by using a monoclonal antibody, and their aggregation by

C Nakayasu1, T Yoshitomi, T Oyamatsu

  • 1Department of Aquatic Biosciences, Tokyo University of Fisheries, Japan.

Veterinary Immunology and Immunopathology
|July 1, 1997
PubMed

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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.