Related Experiment Videos
New types of K+ channels in the colon
1Physiologisches Institut, Albert-Ludwigs-Universität, Freiburg, Federal Republic of Germany.
Wiener Klinische Wochenschrift
|June 27, 1997
Abstract:
The mechanism of epithelial Cl- secretion requires K+ recycling via basolateral ion channels. Two types of K+ channels were identified. A Ca(2+)-activated, and a very small cAMP-regulated K+ channel. Increase of cAMP inhibits the Ca(2+)-activated K+ channel and thus makes small K+ channel the limiting step for cAMP-dependent Cl- secretion.