Upper alveolar carcinoma--a 30 year survey

Area of Science:

• Oral oncology
• Head and neck cancer research

Background:

• Primary malignancy of the upper alveolus is a rare intra-oral carcinoma.
• This study reviews a cohort of 50 patients treated between 1940-1970.

Purpose of the Study:

• To detail the clinical presentation, staging, treatment, and outcomes of primary upper alveolar malignancies.
• To analyze survival rates and discuss treatment rationale for this infrequent cancer.

Main Methods:

• Retrospective review of 50 patients with primary upper alveolar tumors.
• Data collection on patient history, presenting symptoms, tumor extent, lymph node status, treatment modalities, and survival.

Main Results:

• Common symptoms included pain (78%) and swelling (64%).
• Extensive lesions (T3/T4) were present in 52% of patients; 26% had palpable cervical lymph nodes.
• Five-year survival was 44%, and ten-year survival was 24%.

Conclusions:

• Upper alveolar carcinoma often presents with advanced disease and significant metastatic potential.
• Treatment involves surgery and/or radiotherapy, with associated complications.
• Survival rates remain challenging, highlighting the need for effective management strategies.