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Updated: Jul 9, 2026

Models of Bone Metastasis
Published on: September 4, 2012
Invasive versus non-invasive diagnosis of renal bone disease
A Fournier1, R Oprisiu, S Said
1Department of Nephrology, Amiens-University Hospital, France. neph-chu@burotec.fr
Abstract:
At present, bone histomorphometry remains the gold standard for the diagnosis of the various types of renal bone disease. In the search for a non-invasive method of diagnosis, biochemical serum markers of bone remodelling, in addition to serum intact parathyroid hormone and aluminium determinations, have been proposed as the most reliable tools and are at present widely used in clinical practice. Their respective diagnostic values, as separate items and in combined analysis, are thoroughly discussed in the present review.
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