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HLA gene frequencies and migration in an Italian province
A De Silvestri1, M Martinetti, C Daielli
1Dipartimento di Genetica e Microbiologia, Università di Pavia, Italy.
Gene Geography : a Computerized Bulletin on Human Gene Frequencies
|December 1, 1996
Abstract:
HLA class I (HLA-A, HLA-B) and class II (HLA-DR, HLA-DQ) gene frequencies in 6 subareas of Pavia province are calculated in two samples of bone marrow donors. We estimated the degree of genetic differentiation between the 6 sub-areas through the standardized variance FST. On the basis of the island migration model the number of migrants is estimated from FST and compared with the observed migration index in the province according to the 1991 census.