One-stop chest pain clinic can identify high cardiac risk
Insights
Patients with stable chest pain referred for cardiac assessment have a good prognosis, but a significant number experience ongoing symptoms. Clinical criteria effectively identify high-risk individuals for cardiac events.
Area of Science:
- Cardiology
- Clinical Medicine
- Public Health
Background:
- Stable chest pain is a common reason for outpatient cardiac assessment.
- Prognosis and risk stratification are crucial for managing patients with chest pain.
Purpose of the Study:
- To determine the prognosis of patients with stable chest pain undergoing outpatient cardiac assessment.
- To identify factors associated with cardiac chest pain and subsequent cardiac events.
Main Methods:
- A cohort of 660 patients with stable chest pain, normal resting ECG, and no prior cardiac events were followed.
- Data collected included all-cause mortality, non-fatal ischemic events, and coronary revascularization.
- Clinical criteria were used to diagnose cardiac chest pain.
Main Results:
- Cardiac chest pain was diagnosed in 28% of patients, more common in those with recent symptoms, over 50 years old, white, or with hypertension/diabetes.
- Event-free survival at two years was 83.6% for the cardiac group versus 96.6% for the non-cardiac group (p < 0.0001).
- 37% of survivors experienced persistent symptoms, with similar rates in both cardiac and non-cardiac groups.
Conclusions:
- Outpatient cardiac assessment using clinical criteria and non-invasive tests reliably identifies patients at high risk for cardiac events.
- While overall prognosis is good, a substantial proportion of patients experience ongoing symptoms.
- Risk stratification is essential for appropriate management of stable chest pain patients.
Abstract:
The aim of this study was to record prognosis for patients with stable chest pain referred for outpatient cardiac assessment. All 660 patients in the study had a normal resting ECG and no history of myocardial infarction, unstable angina or coronary revascularisation. Main outcome measures were all-cause mortality, non-fatal ischaemic events and coronary revascularisation. Cardiac chest pain was diagnosed in 182 patients (28%). It was more frequent in patients with recent onset of symptoms (< 6 months), patients over 50, white patients, and patients with hypertension or diabetes. The mean follow-up was 622 +/- 338 days. Among survivors, 37% continued to suffer from symptoms (cardiac group: 59 (35.1%); non-cardiac group: 177 (38.4%)). When all hard events were considered, event-free survival (95% confidence interval) for the cardiac group was 90.9% (86.7-95.2%) at six months, 88.9% (84.2-93.6%) at one year, and 83.6% (77.5-89.7%) at two years. Corresponding figures for the non-cardiac group at the same time points were better (p < 0.0001): 98.5% (97.4-99.6%), 97.5% (96.1-99.0%) and 96.6% (94.7-98.5%), respectively. In conclusion, the use of clinical criteria in a cardiac outpatient clinic, backed up by simple non-invasive investigations, can reliably identify a population at high risk of subsequent cardiac events.
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