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Related Experiment Videos

Bladder dysfunction in schizophrenia

W W Bonney1, S Gupta, D R Hunter

  • 1Urology Department, College of Medicine, University of Iowa, Iowa City, USA. William W. Bonney@hitchcock.org

Schizophrenia Research
|June 20, 1997
PubMed
Summary
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Urinary incontinence, particularly urge incontinence, is more common in schizophrenia patients. This suggests a potential neurobiological link between schizophrenia and bladder dysfunction, specifically detrusor hyperreflexia.

Area of Science:

  • Neuroscience
  • Urology
  • Psychiatry

Background:

  • Previous urodynamic studies indicated detrusor hyperreflexia in some schizophrenic patients with incontinence.
  • Schizophrenia shares brain abnormalities with neurological conditions causing urge incontinence and detrusor hyperreflexia.

Purpose of the Study:

  • To investigate bladder dysfunction and incontinence as potential neurobiological correlates of schizophrenia.
  • To assess the prevalence of urinary problems in schizophrenic patients compared to mood disorder patients.

Main Methods:

  • A patient survey was conducted to gather data on urinary problems.
  • Prevalence of incontinence was compared between schizophrenic patients and a control group with mood disorders.

Main Results:

Related Experiment Videos

  • Incontinence was significantly more prevalent in schizophrenic patients than in mood disorder patients.
  • Urge incontinence and general urinary leakage were closely associated with a psychiatric diagnosis of schizophrenia.

Conclusions:

  • The findings suggest that incontinence, potentially due to detrusor hyperreflexia, is prevalent in a subset of schizophrenic patients.
  • Further prospective urodynamic studies are required to validate incontinence as a neurobiological correlate of schizophrenia.