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Updated: Mar 14, 2026
04:23
Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
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[Retroperitoneal hematoma during heparin therapy. Comments on 3 cases]
C Di Rosa1, S Venora, N Monterosso
1Divisione di Chirurgia Generale, Ospedale S. Gravina, Caltagirone, Catania.
Minerva Chirurgica
|April 1, 1997
Summary
Retroperitoneal hemorrhage during heparin treatment may stem from adrenal gland thrombosis, potentially linked to immune responses. Early identification and adrenal gland assessment are crucial for managing this rare, serious complication.
Area of Science:
- Medical Science
- Hematology
- Endocrinology
Background:
- Heparin is widely used for anticoagulation.
- Retroperitoneal hemorrhage is a rare but serious complication.
- Heparin-induced immune phenomena can occur.
Observation:
- A literature review identified a potential thrombotic genesis involving adrenal glands in retroperitoneal hemorrhage during heparin therapy.
- Three cases of this phenomenon were observed over three years.
- The complication is often undervalued due to its rarity.
Findings:
- Retroperitoneal hemorrhage during heparin treatment may be linked to adrenal gland thrombosis.
- This may or may not be correlated with heparin-induced immune phenomena.
- Suspension of heparin is the primary management step, posing a risk.
Implications:
- Underdiagnosis of this heparin complication is possible.
- Knowledge of causes and coagulation status is vital.
- Adrenal gland exploration is recommended for unexplained retroperitoneal hematomas.
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