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Updated: Aug 11, 2026

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
Published on: April 3, 2016
[Effect of active medium on sclera creep]
E D Shchukin1, V N Izmaílova, M M Krasnov
1Moscow State University.
Abstract:
Irreversible stretching (creep) of the eye sclera, regarded as the cause of high myopia, has been studied experimentally. Both dramatic acceleration and appreciable deceleration of the bovine sclera creep have been observed in the presence of some enzymes. Connective tissue creep caused by static and cyclic mechanical stress (gravitation, blood pressure, etc.) can be associated with many age-specific and pathological changes. The authors believe that detection of appropriate creep inhibitors will make it possible to replace surgery with preventive therapy in ophthalmology and cosmetology.

