[Levels of progesterone, estrogen, FSH and LH in galactorrhea of unknown etiology]

Considering the frequent occurrence of idiopathic galactorrhea in the women of fertile age, the hormone status was investigated in 50 patients aged from 20 to 40 years. The FSH, LH, estradiol and progesterone hormones were tested. The hormone level was estimated from venous blood serum in the stage I of menstrual cycle (on 10th day) and in the stage II of cycle (on 22nd day). Patients were divided into 3 groups (related to menstrual cycle): with regular cycle, with irregular and with amenorrhea. Control group consisted of 21 healthy subjects. The changes in levels of FSH and LH were not found in the patients with galactorrheas of unknown etiology. Progesterone level was significantly lower (p < 0.05) in the patients with irregular cycle. Progesterone level was also significantly lower in the patients with amenorrhea and irregular cycle (0.01) and it was significantly raised in the patients with regular cycle (p < 0.05). Significantly higher estrogen (p < 0.05) was found in the patients with amenorrhea, and in the other groups there were no significant changes in estrogen level.