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Reverse micellar extraction of antibiotics from aqueous solutions
N W Fadnavis1, B Satyavathi, A A Deshpande
1Biotransformation Laboratory, Indian Institute of Chemical Technology, Hyderabad, India.
Biotechnology Progress
|July 1, 1997
Abstract:
Several antibiotics such as erythromycin, oxytetracyclin, benzylpenicillin, and actidione were extracted from aqueous buffers into reverse micellar solution of bis(2-ethylhexyl) sulfosuccinate sodium salt (AOT) in isooctane and recovered with high efficiency under mild conditions. Preliminary experiments with oxytetracycline dissolved in a fermentation broth indicate that the antibiotic can be selectively extracted from the broth and recovered efficiently without serious loss of potency.