Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prognostic factors in oligodendrogliomas

L Westergaard1, F Gjerris, L Klinken

  • 1University Clinic of Neurosurgery, Rigshospitalet, Copenhagen, Denmark.

Acta Neurochirurgica
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thoracic intervertebral disc herniation.

Acta neurologica Scandinavica·2009
Same author

Differential effects of insulin detemir and neutral protamine Hagedorn (NPH) insulin on hepatic glucose production and peripheral glucose uptake during hypoglycaemia in type 1 diabetes.

Diabetologia·2009
Same author

Effects of recombinant LH treatment on folliculogenesis and responsiveness to FSH stimulation.

Human reproduction (Oxford, England)·2007
Same author

Idiopathic normal-pressure hydrocephalus: clinical comorbidity correlated with cerebral biopsy findings and outcome of cerebrospinal fluid shunting.

Journal of neurology, neurosurgery, and psychiatry·2006
Same author

Increasing incidence of childhood tumours of the central nervous system in Denmark, 1980-1996.

British journal of cancer·2006
Same author

What is new about idiopathic intracranial hypertension? An updated review of mechanism and treatment.

Cephalalgia : an international journal of headache·2006

Younger patients and those without neurological deficits had significantly better survival rates for cerebral oligodendrogliomas. Radiotherapy showed no impact on outcomes in this patient cohort.

Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Clinical Outcomes Research

Background:

  • Oligodendrogliomas are a type of primary brain tumor.
  • Understanding prognostic factors is crucial for managing these rare tumors.

Purpose of the Study:

  • To analyze outcome predictors in patients with pure cerebral oligodendrogliomas.
  • To evaluate the impact of prognostic factors and radiotherapy on survival.

Main Methods:

  • Retrospective outcome analysis of 96 patients with pure cerebral oligodendrogliomas.
  • Data collected over a 30-year period (1962-1991).
  • Prognostic factors including age, neurological deficit, and tumor grade were assessed.

Main Results:

Related Experiment Videos

  • Youth (under 20 years) was associated with a median survival of 17.5 years.
  • Absence of neurological deficit correlated with a 5-year survival of 43%, versus 5% with deficits.
  • Grade II oligodendroglioma had 46% 5-year survival; Grade III had 10% 5-year survival.
  • Radiotherapy demonstrated no significant effect on survival across all subgroups.

    • Conclusions:

    • Age at diagnosis and neurological status are key prognostic indicators for cerebral oligodendrogliomas.
    • Tumor grade significantly influences patient survival.
    • Current data suggests radiotherapy does not improve survival in this patient population.