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Updated: Oct 26, 2026
A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
Published on: October 20, 2016
Apolipoprotein E genotyping by capillary electrophoretic analysis of restriction fragments
G de Bellis1, G Salani, S Panigone
1Istituto di Technologie Biomediche Avanzate, Segrate, Italy. debellis@itba.mi.cnr.it
Abstract:
We present the genotyping of apolipoprotein (apo) E by means of restriction fragment analysis of amplified genomic DNA by high-performance capillary electrophoresis and a replaceable non-gel-sieving matrix. This procedure streamlines the genotyping of apo E in large-scale population studies because of the automation and speed of capillary electrophoresis.
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