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Protein engineering as a powerful tool for the chemical modification of enzymes
G Moreno-Hagelsieb1, X Soberon
1Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.
Biological Research
|January 1, 1996
Abstract:
This article discusses the techniques of site-specific mutagenesis and protein engineering and their application in the study of enzyme active sites and the mechanism of enzyme action. Particular emphasis is given to beta-lactamase.