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N-type calcium channel blockers from a marine bacterium, Cytophaga sp. SANK 71996
T Morishita1, A Sato, M Hisamoto
1Biomedical Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan.
The Journal of Antibiotics
|June 1, 1997
Abstract:
N-(3-Acyloxyacyl)glycines were isolated as N-type calcium channel blockers from a marine bacterium Cytophaga sp. SANK 71996. The identification and fermentation of the producing strain and structure characterization of N-(3-acyloxyacyl)glycines by spectral analyses and chemical syntheses are described together with their antagonistic activities.