[Evaluation of chemical mutagenic factor in workers]

The authors analysed retrospectively a reproductive function among female workers of chemical plant. The subjects were exposed to mutagenic and carcinogenic chemicals before pregnancy and during early term pregnancy. Occurrence of complications during pregnancy and delivery was significantly higher in the exposed group vs. the reference one. Incidence of congenital abnormalities among children in the exposed group tended to increase. Cytogenetic alterations were reliably more frequent in peripheral WBC and in embryonal tissues obtained during abortions in workers of the plant, if compared to the parameters of the reference group.