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Laryngeal chondrosarcomas: the Mayo Clinic experience
T F Kozelsky1, J A Bonner, R L Foote
1Division of Radiation Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
Journal of Surgical Oncology
|August 1, 1997
Summary
Conservative subtotal laryngectomy may preserve voice long-term for laryngeal chondrosarcoma patients. Recurrences after local excision often allow years of voice preservation before further treatment is needed.
Area of Science:
- Otolaryngology
- Surgical Oncology
Background:
- Laryngeal chondrosarcomas are rare tumors.
- Management strategies are often extrapolated from other sarcoma sites.
Purpose of the Study:
- To evaluate prognostic factors and treatment outcomes for laryngeal chondrosarcomas.
- To assess the efficacy of different surgical approaches.
Main Methods:
- Retrospective analysis of 20 patients treated at Mayo Clinic (1959-1992).
- Review of treatment modalities including local excision, hemilaryngectomy, and total laryngectomy.
Main Results:
- All tumors were low-grade, primarily involving the cricoid cartilage.
- Local recurrence occurred in 30% of patients, mostly after local excision.
- Recurrences typically developed more than 3 years post-initial treatment.
Conclusions:
- Initial conservative subtotal laryngectomy warrants further investigation for voice preservation.
- Local excision may offer significant voice preservation duration, even with late recurrences.