Related Experiment Video

Updated: Aug 17, 2026

Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse
06:04

Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse

Published on: April 27, 2019

Left ventricular diastolic dysfunction in patients with angina decubitus

J Chen1, R Gao, Y Xu

  • 1Cardiovascular Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing.

Chinese Medical Journal
|September 1, 1996
PubMed

Insights

Patients experiencing angina decubitus exhibit impaired left ventricular diastolic function and reduced ventricular compliance. This study highlights diastolic dysfunction as a key factor in angina decubitus episodes.

Area of Science:

  • Cardiology
  • Cardiovascular Physiology

Background:

  • Angina decubitus is a chest pain symptom often associated with cardiac conditions.
  • Understanding the underlying mechanisms of angina decubitus is crucial for effective management.

Purpose of the Study:

  • To investigate the relationship between left ventricular diastolic dysfunction and angina decubitus.
  • To identify potential pathophysiological links between diastolic abnormalities and chest pain during recumbency.

Main Methods:

  • Comparative study involving three groups: healthy controls, coronary artery disease patients without angina decubitus, and patients with angina decubitus and preserved ejection fraction.
  • Left ventriculography (LVG) was performed to assess left ventricular function, including first 1/3 filling fraction (1/3FF) and end-diastolic pressure (LVEDP).

Main Results:

  • A significantly reduced left ventricular first 1/3 filling fraction (1/3FF) was observed in patients with angina decubitus compared to controls and CAD patients without angina decubitus (P < 0.01).
  • Left ventricular end-diastolic pressure (LVEDP) significantly increased post-LVG in angina decubitus patients (P < 0.01), indicating impaired ventricular compliance.
  • No significant changes in LVEDP were noted before and after LVG in control or non-angina decubitus CAD groups.

Conclusions:

  • Patients with angina decubitus demonstrate significant abnormalities in left ventricular diastolic filling.
  • A decrease in left ventricular compliance is a characteristic finding in patients suffering from angina decubitus.
Abstract

More Related Videos

Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs08:19

Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs

Published on: July 12, 2022

Pulsed Wave Doppler Assessment of Diastolic Dysfunction in the ZSF-1 Rat Model of Pulmonary Hypertension Due to Left Heart Disease08:57

Pulsed Wave Doppler Assessment of Diastolic Dysfunction in the ZSF-1 Rat Model of Pulmonary Hypertension Due to Left Heart Disease

Published on: May 22, 2026

Related Concept Videos

Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Angina I: Introduction01:30

Angina I: Introduction

Definition and Symptoms: Angina (angina pectoris) is chest pain or discomfort caused by myocardial ischemia, which occurs when the heart muscle receives insufficient oxygen-rich blood. It typically manifests as pressing, squeezing, or crushing sensations in the chest and may radiate to the shoulders, arms, neck, jaw, or back.Primary Cause: In a healthy state, the coronary arteries can dilate (widen) to increase blood flow and meet the increased oxygen demand during physical activity or...
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
Angina V: Nursing Management01:20

Angina V: Nursing Management

Angina, a symptom of myocardial ischemia, requires a structured nursing management approach to ensure effective care and prevent complications like myocardial infarction. Comprehensive nursing care involves assessing, diagnosing, planning, implementing interventions, and evaluating outcomes, all tailored to the individual patient's needs.Patient AssessmentNursing assessment begins with a detailed subjective evaluation of symptoms, which typically include chest pain or pressure radiating to the...
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...