Related Experiment Video
Updated: Aug 28, 2026

Automated Measurement of Pulmonary Emphysema and Small Airway Remodeling in Cigarette Smoke-exposed Mice
Published on: January 16, 2015
[Comparative observation on the relationship between the MEFV and the visual inspection of small airway]
Objective:
To compare the relationship between the MEFV and the visual inspection of small airway.
Methods:
According to the result on small airway function test (MEFV), the patients were divided into two group: MEFV abnormal group and MEFV normal group. Their bronchus and peripheral airway were observed with bronchofiberscope and ultra-thin bronchofiberscope. The visual appearance of the airways was scored in the light of the presence or absence of erythema, edema, secretions, etc.
Results:
The score of visual appearance observed or bronchitis index (BI) in small airway was 7.7 +/- 0.8 (BI: 3.0 +/- 0.8) and 4.7 +/- 1.6 (BI: 1.5 +/- 0.5) respectively in MEFV abnormal group and in MEFV normal group, namely the score in MEFV abnormal group was significantly higher than that of normal group (P < 0.01). The degree of pathological change in small airway was significantly correlated with the results of V25, V50, r = -0.6271, (P < 0.05) and r = 0.6964, (P < 0.02).
Conclusion:
The abnormal of MEFV may reflect inflamative pathological changes of small airway.
Related Concept Videos
Assessment of Airway, Skin Color, and Use of Accessory Muscles
Introduction
The initial evaluation of a patient's respiratory system...
Physical Assessment of the Respiratory Tract II: Inspection
Chest Configuration
The chest configuration can...

