[A pathological analysis of 180 cases of vascular malformation of brain]

180 cases of vascular malformation in brain (BVM) including 156 cases of brain biopsy and 24 autopsy cases were examined with routine pathological methods. The attempt of this study is to realize the pathological change and incidnce of each type and to find out the main cause of hemorrhage in BVM. According the morphological characteristics, 180 cases of BVM were classified into five types. They are: arteriovenous type 159 cases, venous type 3 cases, cavernous type 6 cases, capillary telangiectasis 1 case, and mixed type 11 cases. Hemorrhage was the most common clinical manifestation and main cause of death in BVM. The mechanism of hemorrhage may be due to either hemodynamic disturbance in local area or changes of the blood vessel wall. Besides these, there are five cases of BVM accompanied with brain tumor. They may be two independent diseases occurred in the same person. No relationship was found between the occurrence of these 2 entities.