Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Adrenoleukodystrophy: phenotype, genetics, pathogenesis and therapy

H W Moser1

  • 1Kennedy Krieger Institute, Baltimore, MD 21205, USA.

Brain : a Journal of Neurology
|August 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A PEX10 defect in a patient with no detectable defect in peroxisome assembly or metabolism in cultured fibroblasts.

Journal of inherited metabolic disease·2009
Same author

Magnetization transfer MRI demonstrates spinal cord abnormalities in adrenomyeloneuropathy.

Neurology·2005
Same author

Spectroscopic evidence of cerebral axonopathy in patients with "pure" adrenomyeloneuropathy.

Neurology·2005
Same author

Analysis of MRI patterns aids prediction of progression in X-linked adrenoleukodystrophy.

Neurology·2003
Same author

Clinical and electrophysiological improvement of adrenomyeloneuropathy with steroid treatment.

Journal of neurology, neurosurgery, and psychiatry·2003
Same author

MRI and proton MRSI in women heterozygous for X-linked adrenoleukodystrophy.

Neurology·2003
Same journal

Fus-depleted oligodendrocytes reduce neuronal damage and Alzheimer's disease progression in the AppNL-G-F mouse.

Brain : a journal of neurology·2026
Same journal

Cervical lymph node biomarkers in neurodegeneration.

Brain : a journal of neurology·2026
Same journal

Lower motor neuron disorders: time for a closer look.

Brain : a journal of neurology·2026
Same journal

Reply: Cervical lymph node biomarkers in neurodegeneration.

Brain : a journal of neurology·2026
Same journal

Propionic acid and neurofilament light chain in multiple sclerosis.

Brain : a journal of neurology·2026
Same journal

Propionic acid in multiple sclerosis: a phase 2b, double-blind, randomized placebo-controlled trial.

Brain : a journal of neurology·2026
See all related articles

This lecture honors Gordon Holmes

Area of Science:

  • Neurology
  • Neuroscience
  • Medical History

Background:

  • Review of Gordon Holmes' collected works, spanning 174 publications over 55 years.
  • Holmes' research encompassed neuroanatomy, neuropathology, and disorders of the adrenal cortex, spinal cord, cerebellum, and cerebral cortex.
  • The lecture is inspired by the late Anita Harding, who provided guidance and encouragement.

Purpose of the Study:

  • To follow Gordon Holmes' methodology of stepwise clinical problem analysis.
  • To apply observational and technical methods to clarify clinical issues.
  • To advance knowledge in specific neurological disorders, the nervous system, and human biology, aiming for improved therapies.

Main Methods:

  • Stepwise analysis of clinical problems.

Related Experiment Videos

  • Patient observation.
  • Application of clarifying techniques.

    • Main Results:

    • The lecture serves as a tribute and a methodological guide.
    • It highlights the breadth of Gordon Holmes' contributions to neuroscience.
    • It emphasizes a systematic approach to understanding and treating neurological conditions.

    Conclusions:

    • The systematic approach exemplified by Gordon Holmes remains crucial for advancing neurological understanding.
    • Interdisciplinary research in neuroanatomy and neuropathology is vital.
    • The pursuit of knowledge aims for enhanced patient therapy and a deeper comprehension of the nervous system.