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Related Experiment Videos

Sedation with ketamine during cataract surgery

U Cugini1, P Lanzetta, P Nadbath

  • 1Department of Anesthesiology (Cugini, Nadbath), University of Udine, Italy.

Journal of Cataract and Refractive Surgery
|June 1, 1997
PubMed
Summary

Low-dose ketamine in cataract surgery anesthesia improved patient comfort without affecting intraocular pressure (IOP). This sedation-analgesia regimen offers a safe and effective option for ophthalmic procedures.

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Area of Science:

  • Ophthalmology
  • Anesthesiology
  • Pharmacology

Background:

  • Cataract surgery requires effective sedation and analgesia.
  • Assessing the impact of anesthetic agents on cardiovascular and ocular parameters is crucial.

Purpose of the Study:

  • To evaluate the cardiovascular and ocular effects of a low-dose sedation-analgesia regimen including ketamine for cataract surgery.
  • To determine if ketamine influences intraocular pressure (IOP) and patient comfort during the procedure.

Main Methods:

  • Eighty patients undergoing cataract surgery were randomized into two groups.
  • One group received droperidol, diazepam, and ketamine; the control group received droperidol and diazepam without ketamine.
  • Cardiovascular parameters (heart rate, arterial pressure) and IOP were measured before and after sedation.

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Main Results:

  • Ketamine administration did not significantly alter IOP.
  • Systolic arterial pressure decreased in both groups, with a more pronounced drop in the control group.
  • Patients receiving ketamine reported significantly less pain during and after anesthesia compared to the control group.

Conclusions:

  • Low-dose ketamine, as part of a sedation-analgesia regimen, is safe for cataract surgery.
  • Ketamine effectively reduces pain perception without negatively impacting IOP.
  • This regimen facilitates comfortable anesthesia and surgery completion.