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Related Experiment Videos

[Functional insulin therapy and pregnancy]

P Fasching1

  • 1Klinische Abtellung für Endokrinologie und Stoffwechsel, Universitäts-klinik für Innere Medizin III, Wien.

Wiener Medizinische Wochenschrift (1946)
|January 1, 1997
PubMed
Summary
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Optimal management of pregnant women with type-I diabetes mellitus (T1DM) in specialized centers ensures good outcomes. Achieving near-normal blood glucose control with functional insulin therapy minimizes maternal and fetal risks, similar to healthy pregnancies.

Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Neonatology

Background:

  • Type-I diabetes in pregnancy presents unique challenges for maternal and fetal health.
  • Specialized care centers are crucial for managing pregnant individuals with T1DM.
  • Pre-existing diabetic complications significantly increase pregnancy risks.

Purpose of the Study:

  • To outline the essential components of optimal care for pregnant women with T1DM.
  • To emphasize the importance of multidisciplinary collaboration for managing T1DM pregnancies.
  • To highlight strategies for achieving "near-normoglycemic" control during pregnancy.

Main Methods:

  • Functional insulin therapy using a basal-bolus regimen.
  • Frequent self-monitoring of blood glucose (more than 6 times daily).

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  • Close collaboration between obstetricians, diabetologists, and neonatologists.
  • Main Results:

    • Optimal preconceptional control and guidance lead to maternal and fetal risks comparable to healthy pregnancies.
    • Near-normoglycemic control is achievable with intensive insulin management and frequent glucose monitoring.
    • Non-compliance and severe diabetic complications identify high-risk pregnancies.

    Conclusions:

    • Pregnant women with T1DM require management in experienced diabetes centers with multidisciplinary teams.
    • Intensive insulin therapy and frequent glucose monitoring are key to successful pregnancy outcomes.
    • Preconceptional counseling and specialized care are mandatory for high-risk T1DM pregnancies.