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[Ovarian Leydig cell tumor]

P Tönnies¹, M L Mlynek-Kersjes, J Gellén

¹Frauenklinik, Stiftung Krankenhaus Bethanien für die Grafschaft Moers.

Zentralblatt Fur Gynakologie

|January 1, 1997

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A rare Leydig cell tumor of the ovary was diagnosed in a 73-year-old woman. Surgical removal of the tumor resolved long-standing signs of virilization.

Area of Science:

Gynecologic Oncology
Endocrinology
Pathology

Background:

Leydig cell tumors are rare ovarian neoplasms, typically presenting with signs of androgen excess.
This case highlights a delayed diagnosis of an ovarian Leydig cell tumor despite prolonged virilization symptoms.

Observation:

A 73-year-old woman presented with a history of unexplained virilization.
The ovarian Leydig cell tumor was incidentally discovered post-hysterectomy with bilateral salpingo-oophorectomy.

Findings:

Histopathological examination confirmed a well-differentiated Leydig cell tumor of the ovary.
Post-operative regression of androgenic symptoms confirmed the tumor as the cause of virilization.

Implications:

Related Experiment Videos

This case underscores the importance of investigating androgenic symptoms, even in elderly patients.

Early diagnosis and surgical management of ovarian Leydig cell tumors are crucial for reversing virilization.