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Chronic Salmonella Infected Mouse Model
Published on: May 31, 2010
Chronic health effects of microbial foodborne disease
V K Bunning1, J A Lindsay, D L Archer
1Division of Virulence Assessment, Food and Drug Administration, Laurel, MD, USA.
Abstract:
The acute effects of foodborne disease are sometimes not the end of the illness. Several significant foodborne pathogens are capable of triggering chronic disease, and even permanent tissue or organ destruction, probably via immune mechanisms. Arthritis, septic and reactive, inflammatory bowel disease, haemolytic uraemic syndrome, Guillain-Barré syndrome, and possible several autoimmune disorders can be triggered by foodborne pathogens or their toxins. Research is needed to more fully understand the mechanisms by which the immune system is inappropriately activated by these common foodborne disease-causing agents.
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