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[Heart rate changes in propofol anesthesia--relation with excitatory movements]
I Nakatsuka1, J Takeda, K Fukushima
1Department of Anesthesiology, Inadanoborito Hospital, Kawasaki.
Masui. the Japanese Journal of Anesthesiology
|August 1, 1997
Summary
Propofol anesthesia can cause excitatory movements and heart rate acceleration. Heart rate monitoring can detect these movements, even during muscle relaxation.
Area of Science:
- Anesthesiology
- Pharmacology
Context:
- Propofol is a common intravenous anesthetic agent.
- Excitatory movements and associated autonomic changes during propofol anesthesia are not fully understood.
Purpose:
- To investigate the relationship between excitatory movements and heart rate acceleration during propofol anesthesia.
- To assess the influence of muscle relaxants on these phenomena.
Summary:
- Four patients exhibited simultaneous heart rate acceleration and excitatory movements during propofol anesthesia.
- These movements persisted despite muscle relaxation with vecuronium in three patients.
- Heart rate acceleration ceased in one patient after midazolam administration and in another after reducing propofol infusion rate.
Impact:
- Heart rate acceleration appears closely linked to propofol-induced excitatory movements.
- Heart rate monitoring is a valuable tool for detecting subclinical excitatory movements during muscle relaxation.