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Sensitivity of antibacterials of Staphylococcus aureus isolated from impetigo patients
1Division of Dermatology, Kansai Medical University, Kori Branch Hospital, Osaka, Japan.
Abstract:
We measured the sensitivity to antibacterials of Staphylococcus aureus isolated from impetigo lesions during one year (from July 1994 to July 1995). The largest number of strains was resistant to gentamicin, followed by erythromycin. Few methicillin-resistant S. aureus strains were isolated and few strains were resistant to more than one drug. We conclude that nadifloxacin and tosufloxacin are likely to be most effective against S. aureus, but fusidic acid is more suitable for the treatment of children.
Insights
This study assessed Staphylococcus aureus antibacterial sensitivity in impetigo patients. Gentamicin and erythromycin resistance were most common, with few multidrug-resistant strains found.
Area of Science:
- Microbiology
- Dermatology
- Infectious Diseases
Background:
- Impetigo is a common bacterial skin infection.
- Staphylococcus aureus is a primary causative agent of impetigo.
- Understanding antibiotic resistance patterns is crucial for effective treatment.
Purpose of the Study:
- To determine the in vitro sensitivity of Staphylococcus aureus strains isolated from impetigo lesions to various antibacterials.
- To identify prevalent resistance patterns in Staphylococcus aureus relevant to impetigo treatment.
Main Methods:
- Bacterial isolates of Staphylococcus aureus were collected from impetigo lesions over a one-year period (July 1994-July 1995).
- Antimicrobial susceptibility testing was performed on isolated strains.
- Resistance to specific antibiotics, including gentamicin, erythromycin, and methicillin, was assessed.
Main Results:
- The highest rates of resistance were observed for gentamicin and erythromycin.
- Few strains of methicillin-resistant Staphylococcus aureus (MRSA) were identified.
- Most isolated strains showed sensitivity to more than one antimicrobial agent.
Conclusions:
- Nadifloxacin and tosufloxacin demonstrate potential efficacy against Staphylococcus aureus in impetigo.
- Fusidic acid is suggested as a suitable treatment option for impetigo, particularly in pediatric cases.
- Monitoring antibiotic resistance is essential for guiding impetigo therapy.